Endocrine Abstracts

Higher serum TSH has been recently postulated as a predictor of thyroid malignancy in nodular thyroid disease. In addition, some reports have demonstrated its association with more advanced stages of differentiated thyroid cancer (DTC).Material and methods: We collected retrospectively preoperative serum TSH from patients who underwent total thyroidectomy in the period 2005–2011 in a single tertiary center. We recorded demographic data, nodule numbe...

Current guidelines recommend measurement of rhTSH-stimulated Tg, with neck ultrasound 6–12 months after the initial therapy for DTC (Total thyroidectomy plus 100 mCiI131 ablation of the thyroid bed). Uncertainty persists regarding whether the subsequent follow up should be based on measurement of basal serum Tg or whether rhTSH-stimulated Tg should be performed and at what frequency. The aim of our study was to evaluate the utility of repeated rhTSH-stimulated Tg.<p c...

Troisier’s sign names a visible left cervical adenopathy (Virchow’s node) as the first sign of a pancreatic tumor, mainly adenocarcinomas, by dissemination through the thoracic duct. Neuroendocrine tumors (NET) of the ampulla of Vater are extremely rare, no more than 2% of ampullary malignancies, and account for <0.3% of all gastrointestinal NETs.A 59–year old woman presented with an enlarging painless left cervical node. Ultrasonograp...

Objectives: SGLT2 inhibitors and GLP1 analogs are the treatment of choice after metformin in patients with type 2 diabetes (DM2) and overweight-obesity (OB). The aim of this study is to analyze the effectiveness and safety of these treatments alone or in combination.Methodology: This is a retrospective observational study in the usual clinical practice. We analyzed the effects of SGLT2 inhibitors and GLP1 analogs treatments in patients with DM2 and OB wh...

Introduction: Amiodarone is an antiarrhythmic drug whose high iodine content may influence thyroid function. The first line treatment of amiodarone-induced hyperthyroidism (AIH) is mainly medical. Plasmapheresis has been used in cases of antithyroid intolerance or refractory hyperthyroidism, although clinical experience is poor.Clinical case: We present a case of a patient with structural heart disease and severe AIH refractory to medical treatment who r...